Effective sedation is crucial for pediatric patients undergoing CT scans, however the use of intramuscular dexmedetomidine for this purpose hasn't been extensively explored. Our aim was to assess the efficacy and safety of intramuscular dexmedetomidine for sedation and anxiety relief during CT imaging in pediatric patients. We reviewed 30 cases of children aged 4-14 undergoing non-contrast CT Scan, who received single or multiple doses of 1 mcg/kg intramuscular dexmedetomidine to achieve a minimum Ramsay sedation score of 4.We analyzed patient demographics, diagnoses, vital signs, adverse events, and outcomes. Our findings indicate that all 30 children successfully underwent CT Scan under intramuscular dexmedetomidine sedation, with an average dose of 2.55±0.55 μg and an average time to achieve a minimum Ramsay sedation score of 4 of 14.07±0.88  minutes. Importantly, there were no significant changes in heart rates and mean arterial pressures from baseline values. In conclusion, intramuscular dexmedetomidine proves to be an effective and safe sedation option for pediatric patients undergoing non-contrast CT scan, offering an alternative approach that does not require intravenous access