International Journal of Medical and Pharmaceutical Research
2024, Volume-5, Issue-6 doi: https://doi.org/10.5281/zenodo.14436563
Original Research Article
To Study the Hematological Parameters and Risk Factors Associated with Febrile Seizure in Children in Sri Siddartha Medical College and Hospital Tumkur
Published
Dec. 13, 2024
Abstract

Background: Febrile seizure is the common type of seizure disorder of childhood occurs in an age-specific manner, usually between 6 months to 5 years of age. It is associated with a fever of temperature 38.0℃ or higher, and presents without any evidence of definite causative diseases, such as metabolic abnormality or central nervous system (CNS) infection. Febrile seizure may be simple or complex. The prevalence of febrile seizures among different communities is between 2-4%, About 4 out of 10 children who had febrile seizure will get them later at some stage, although the risk factors differ from one child to other child. In most of the patients, fever is due to upper respiratory system and urinary tract infection. Objectives: 1) To identify the Risk factors associated with febrile seizure. 2) To analyse the CBC and CRP levels in febrile seizure. Methodology: This study was a cross sectional study. All the In patient and Outpatient children in the department of paediatrics who are diagnosed with febrile seizure and satisfying inclusion criteria was enrolled for the study after obtaining the written informed consent at Sri Siddhartha Medical College And Research Centre, Tumkur. The sample size considered is 70 cases. The study included children aged between 6 months to 5 years of age and excluded the children with seizures other than febrile seizure. Results: The study included 75 children with febrile seizure, Majority of the population had high grade fever (> 101 F). In this present study URTI was found to be the cause the fever leading to the seizures, almost all the children presented with GTCS. Only two had partial convulsions. The onset of seizure was within 24 hours of the onset of the febrile episode in 43/75children. There was a positive family history in 22/75 patients. The correlation of the previous history and the type of seizure, there was no significance. 40/75 of the patients had features of anaemia. The association with type of seizure was found to be statistically significant. In more than half the patients, we noted an elevated total leucocyte count. In 2/3rd of the patients, CRP was observed to be elevated. Conclusion: The most prevalent kind of febrile seizure was the simple febrile seizure. While a minority had positive family history and past history, we noted that majority had coryza that triggered the episode. Anaemia was also identified to be a significant risk factor for our study.

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