International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-3 doi: 10.5281/zenodo.7956578
Original Article
To Study the Effectiveness of Mofified Triple Test Score in Differentiating Benign Versus Malignant Breast Diseases
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Published
May 22, 2023
Abstract
Background: Early diagnosis and accurate evaluation of breast lumps are crucial for optimal management and improved patient outcomes. The Modified Triple Test (mTT) combines clinical examination, high-resolution ultrasonography (USG), and fine needle aspiration cytology (FNAC) to diagnose breast lesions. This study aimed to assess the effectiveness of mTT in evaluating breast lumps and to compare its results with the standard Triple Test done elsewhere worldwide. Methods: The study included 50 patients presenting with breast lumps. The mTT score was calculated for all cases, and the sensitivity, specificity, and positive predictive value (PPV) of each diagnostic method were determined. Results: The sensitivity and specificity of clinical examination were 83.87% and 78.95%, respectively. USG showed a sensitivity of 87.10% and specificity of 78.95%, with a PPV of 90%. FNAC demonstrated the highest sensitivity (100%) and specificity (89.47%), with a PPV of 93.94%. Among patients below 40 years, 84.37% had benign lesions, while 77.78% of patients above 40 years had malignant lesions. Right-sided breast lesions were more common (42%) than left-sided (34%), with bilateral lesions found in 24% of cases. The upper outer quadrant was the most commonly involved site (74%).In our study, Axillary Lymphadenopathy was seen in 29 cases. 19 Cases were found to be malignant. Conclusion: The Modified Triple Test is an effective and reliable method for evaluating breast lumps. FNAC showed the highest sensitivity and specificity among the diagnostic methods studied. The mTT can be a valuable diagnostic tool in the assessment of breast lumps, particularly in low-resource settings.
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