International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-3 doi: 10.5281/zenodo.7951178
Original Article
Study of Correlation Between Serum Albumin and Hba1c in Type 2 Diabetes Mellitus Patients
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Published
May 19, 2023
Abstract
Background: ADA recommends HbA1c testing in diabetic patients as initial assessment and a part of continuing care. HbA1c reflects average glycemic status over 2-3 months and predicts diabetic complications. In diabetes, albumin synthesis, secretion is decreased due to insulin deficiency. It is expected that albumin levels decrease in diabetes and may affect plasma protein glycation and HbA1c is a measure of high glucose levels [5-7]. Despite a significant negative correlation between serum albumin and HbA1c in diabetes mellitus, serum albumin is not monitored in diabetes. Objectives: To study the correlation between Hba1c and serum albumin levels in type 2 diabetes mellitus patients. Methods: 50 Study participants with Diabetes mellitus attending K R hospital were included in this study. FBS, PPBS, HbA1c and serum albumin were estimated Results: The mean age of the subjects was 62.43 ± 11.58 years. 58% of the study subjects were males. The mean HbA1c and serum albumin of the subjects was 7.89±0.54 and 3.35±0.71 respectively. HbA1c was found to be negatively correlated with serum albumin level. The association was found to be statistically significant between HbA1c and serum albumin. Conclusion: Serum albumin can mirror insulin secretory reserve, which influences glycemic control and ketosis risk.
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