International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-2 doi: 10.5281/zenodo.7899964
Original Article
Study of Clinical Profile And fetomaternal Outcomes in Hepatitis B Infection
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Published
April 30, 2023
Abstract
Objective: To study the prevalence as well as maternal and fetal outcome in pregnant women with hepatitis B infection. Material and Methods: A Prospective observational study was conducted in the department of Obstetrics and Gynaecology for a period of 2 years from November 2020-October 2022 in Government Medical College, Aurangabad. This study was done on 190 pregnant women with hepatitis B infection who delivered in our institute. A preset case proforma was used to note all the details about the cases. Socio-demographic profile, obstetric, medical and surgical history, as well as history pertaining to HBV infection and high-risk behaviours was extracted in detail from them. Patients were delivered in special place (septic labor room) to avoid any risk of infection using all aseptic precautions. The maternal and fetal outcomes were noted. Results: In our study, the prevalence of hepatitis B infection was found out to be 0.5%. Most common age group in present study was 21-25 (52.63 % cases) years with mean age of 24.37 years.60.52 % cases were from rural area .40.37 % of women had secondary education. 44.73% of the cases were unbooked.53.68% of cases were primigravida with only 1.9 % having a high viral load.75.78% of the cases in our study were asymptomatic, with no identifiable risk factor for transmission in 76.84%.71.05 % of the women did not develop any complications associated with hepatitis B in intrapartum period. 94.73%of women did not develop complications pertaining to Hepatitis B in postpartum period, while 1% of the cases developed hepatic flare. 81.5% women delivered vaginally, while 18.42% of them had a LSCS. Among the 190 babies, 82.10% babies were healthy at birth with a APGAR score of >7 and stayed with their mother, 15.78% babies were admitted in NICU out of which 7.36 % were preterm. Conclusion: Hepatitis B infection during pregnancy is asymptomatic most of the times, however routine screening of all pregnant women will help in detection of this infection. This infection adversely affects some pregnant females, and also has chances of perinatal transmission. So, appropriate measures should be undertaken to reduce the adverse maternal and neonatal outcomes.
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