Central venous access is a common and essential procedure performed in many clinical settings for a variety of indications. Like any other procedure Central lines are not without risk, and there are a multitude of complications that are associated with their placement. Complications can present in an immediate or delayed manner and vary based on type of central venous access. These complications can cause a significant healthcare burden in cost, hospital days, and patient quality of life. Advances in imaging, access technique, and medical devices have reduced and altered the types of complications encountered in clinical practice; but most complications still center around vascular injury, infection, and misplacement. Recognition and management of central line complications is important when caring for patients with vascular access, but prevention is the ultimate goal. This research article  discusses about the  number of patient who had various complications of central line which has been observed in age group of 12 to 30yrs, 30 to 50 yrs, and 50 and above yrs in past one year in Hamidia Hospital Bhopal.