Human immuno deficiency virus is RNA retro virus. HIV infection can be transmitted by four ways, It can be transmitted from infected mother to her fetus during pregnancy, during delivery and through breastfeeding.
Transmission of Treponema pallidum infection from syphilitic mother to her fetus through Placenta occurs at any stage of pregnancy. Transmission of Hepatitis B virus by vertical transmission to fetus occurs mostly in first trimester. Transmission of Hepatitis C infection occurs mainly by post transfusion in prenatal period. AIM: the aim of the study is to assess the sero prevalence of HIV, HBV, HCV and Syphilis among pregnant women attending antenatal OP and Labor ward in GGH, Rajamahendravaram. Methods: This study was conducted by using standard guidelines of NACO And CLSI. The data was statistically analysed. Results: A total number of 2400 antenatal women are screened for HIV, HBV, HCV and Syphilis infection. Among those second gravida was higher with 50%, Most of the women from rural area, Seroprevalence of HIV is 0.66% HBV is 1.75% HCV is 0.041% and Syphilis is 0.04%.