Introduction: The mesenteric small intestine diagnostic study is not principally dependent on endoscopic viewing. Increased speed and resolution of MDCThave made it a first line modality for the examination of small bowel diseases. MDCT Enterography differs from routine abdomino-pelvic CT as it makes use of thin sections and large volumes of enteric contrast material for better display of the small bowel lumen and wall, permits excellent assessment of hyper vascular lesions and hyper enhancing segments. Objectives: 1) To study the radiological features of small intestinal diseases. 2) To draw a systematic patterned approach to narrow down the differential diagnosis based on radiological findings. 3) To evaluate the diagnostic accuracy of MDCT Enterography with clinical, histopathological and surgical correlation. Materials and Methods: Total 40 cases of suspected small intestinal disease referred to underwent MDCT Enterography at Department of Radio-Diagnosis of SSIMS & RC, Davangere from the year June 2023 to December 2024.Imaging was done on a 128slice MDCT scanner manufactured by GE MDCT scan machine.Results:The common MDCT Enterography findings were distal bowel involvement, mucosal layer involvement, and homogeneous wall enhancement. Focal involvement was seen in majority of patients with mild mural thickness. Small bowel obstruction was commonest cause, followed by abdominal tuberculosis. Conclusion:MDCT Enterography is an efficient in detecting small bowel pathologies. Distal bowel and mucosal layer involvement, homogeneous wall enhancement, focal involvement with the mild mural thickening are most common findings. Small bowel obstruction and abdominal tuberculosis being the most common diseases.