International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-3 doi: 10.5281/zenodo.8053814
Original Article
Recurrence Patterns of Breast Cancer in Elderly Women Following Breast Conservation Surgery or Mastectomy without Adjuvant Radiotherapy or Chemotherapy
 ,
Published
June 19, 2023
Abstract
Background: This research aims to investigate the recurrence patterns of breast cancers in elderly women (>65 years) treated with breast-conserving surgery (BCS) or mastectomy alone, and compare the treatment outcomes with those having BCS/mastectomy plus adjuvant radio or chemotherapy. Methods: The study was conducted on 75 patients divided into two groups: Group-1 consisted of 50 patients who underwent BCS/MRM without adjuvant chemotherapy or radiotherapy, only receiving adjuvant hormonal therapy, while Group-2 was comprised of 25 patients who underwent BCS/MRM and received adjuvant chemo and/or radiotherapy, with or without hormonal therapy. Results: The recurrence rates were 10% and 8% in Group-1 and Group-2 respectively. The risk ratio was 1.07, indicating a minor difference in the risk of recurrence between the two groups, which was not statistically significant (p>0.05). The mean time to recurrence was marginally higher in Group-1 (15.25 +/- 3.77 months) compared to Group-2 (14.33 +/- 3.05 months). Conclusion: The study reveals no significant difference in breast cancer recurrence rates in elderly women post BCS/mastectomy whether adjuvant therapy was administered or not. This challenges traditional protocols and argues for the reconsideration of the necessity and benefits of adjuvant therapies in this demographic.
Recommended Articles
Loading Image...
Volume-4, Issue-3
Citations
63 Views
23 Downloads
Share this article
License
Copyright (c) International Journal of Medical and Pharmaceutical Research
pdf Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
All papers should be submitted electronically. All submitted manuscripts must be original work that is not under submission at another journal or under consideration for publication in another form, such as a monograph or chapter of a book. Authors of submitted papers are obligated not to submit their paper for publication elsewhere until an editorial decision is rendered on their submission. Further, authors of accepted papers are prohibited from publishing the results in other publications that appear before the paper is published in the Journal unless they receive approval for doing so from the Editor-In-Chief.
IJMPR open access articles are licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. This license lets the audience to give appropriate credit, provide a link to the license, and indicate if changes were made and if they remix, transform, or build upon the material, they must distribute contributions under the same license as the original.
Logo
International Journal of Medical and Pharmaceutical Research
About Us
The International Journal of Medical and Pharmaceutical Research (IJMPR) is an EMBASE (Elsevier)–indexed, open-access journal for high-quality medical, pharmaceutical, and clinical research.
Follow Us
© Copyright IJMPR | All Rights Reserved