Background: Suicide remains a significant global public health issue, with over 700,000 deaths annually, predominantly in low- and middle-income countries like Bangladesh. Despite its rising prevalence, suicide in Bangladesh is under-researched due to stigma and limited surveillance. Interpersonal conflicts, particularly intimate partner relationship (IPR) issues such as domestic violence, separation, and infidelity, are significant contributors to suicidal behavior. Young adults are especially vulnerable due to social and emotional challenges, compounded by cultural taboos surrounding relationship struggles. Aim of the study: This study aims to assess the prevalence and types of suicide cases associated with intimate partner relationship issues among death cases reported at Dhaka Medical College. Methods: This cross-sectional descriptive study was conducted in the Forensic Medicine Department of Dhaka Medical College from June 2023 to July 2024. A total of 200 confirmed suicide cases with sufficient relational background were purposively selected. Data were collected using a structured checklist based on medico-legal records, autopsy reports, and police inquest forms. They included demographic, clinical, and relational variables such as intimate partner problems (IPP) and intimate partner violence (IPV). Data were analyzed using SPSS version 26.0, with results presented through descriptive statistics. Ethical approval was obtained from the Institutional Review Board of Dhaka Medical College. Result: In this study, the majority were males (60%) and aged 18–25 (35%). Half of the victims were married, and 40% had a history of mental illness. Prior suicide attempts were noted in 30%, and tobacco use was the most common substance (30%). Hanging (45%) and poisoning (35%) were the leading suicide methods. Notably, 60% of suicides were associated with intimate partner problems (IPP), and 40% involved intimate partner violence (IPV), including relationship conflicts, infidelity, separation, and domestic abuse, highlighting the critical role of interpersonal dynamics in suicide cases. Conclusion: Intimate partner relationship issues were major contributors to suicide, affecting primarily young adult males. Hanging and poisoning were standard methods, with mental illness, prior attempts, and substance use prevalent. The findings emphasize the need for targeted mental health services, relationship counselling, and intimate partner violence prevention strategies.