Background: Premature rupture of membranes (PROM) is the rupture of the fetal membranes before the onset of labor. Premature rupture of membranes (PROM) is one of the most common problems in Obstetrics complicating approximately 5-10% of term pregnancies. Complications related to PROM are reparatory distress, necrotizing enterocolitis, intraventricular hemorrhage and sepsis. The knowledge of incidence of early onset sepsis in relation to PROM and its effect on neonatal outcome is essential in order to prevent the neonatal morbidity and mortality. Methods: The present study was a single-center, observational Study conducted on patients admitted with neonates, mother with rupture of membrane. Irrespective of treatment and in the department of Paediatrics, Sri Siddhartha Medical College hospital and Research Centre, Tumkur from January 2020 to July 2022. Prior initiation of the study obtained Ethical and Research Committee clearance from Sri Siddhartha Medical College hospital and Research Centre, Tumkur. During present study total 165 neonates were reviewed in OPD/IP, among 85 patients were enrolled into the study according present study inclusion criteria and 80 patients were excluded according exclusion criteria. Results: Most neonates had maternal age of 21-25 years (51.76%).Most neonates in the study were born in primigravida (61.18 %).Most neonates were born with booked appointments (80 %). Most subjects were born through normal vaginal delivery (57.65 %). Most of the study subjects had gestational age of 35-36 weeks (41.17%). Most subjects had latency period of 0-24 hours (56.47 %). Most of the subjects were males (54.11 %). Most of the subjects' weight at birth was 2-2.5 kg (51.76 %). Most of the subjects required admission into NICU (56.47 %). Common neonatal complication in PPROM encountered in our study jaundice; respiratory distress syndrome; hypoglycemia; hypothermia; septicemia and IVH. Most of the subjects had no complications (65.88 %). Common complications occurred during hospital stay in the present study were decreased activity, fever, feeding difficulties, apenic spells, abdominal distension, convulsions and bleeding. Most of the subjects had normal CBC reports (64.71 %). Most of the subjects had normal CRP reports (72.94 %).