International Journal of Medical and Pharmaceutical Research
2026, Volume-7, Issue 2 : 3293-3297
Research Article
Optimal Combined Anteversion in Total Hip Replacement for Indian Population: A Prospective Functional Outcome Study
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 ,
Received
March 21, 2026
Accepted
April 9, 2026
Published
April 23, 2026
Abstract

Background: Combined anteversion (CA), defined as the sum of acetabular and femoral anteversion, is a key determinant of stability in total hip replacement (THR). Traditional “safe zones” have been derived from Western populations and may not reflect functional demands of Indian patients [1,2].

Aim: To determine the optimal combined anteversion range in Indian patients undergoing THR and its correlation with functional outcomes and lifestyle activities.

Methods: A prospective observational study was conducted on 82 patients undergoing primary THR. Patients were grouped based on CA (<25°, 25–50°, >50°). Functional outcomes were assessed using Harris Hip Score (HHS), WOMAC score, and lifestyle activities.

Results: Patients with CA between 25–50° demonstrated significantly better functional outcomes (p < 0.001). Squatting ability was highest in this group. Dislocation occurred more frequently in extreme CA groups.

Conclusion: Optimal CA for Indian patients appear to lie between 30–55 degree, suggesting the need for population-specific targets.

Keywords
INTRODUCTION

Total hip replacement (THR) is widely regarded as one of the most successful orthopaedic procedures [18]. Implant positioning plays a critical role in determining postoperative stability and function.

 

The concept of acetabular safe zones was first described by Lewinnek et al. [1]; however, dislocations continue to occur even within these zones [9]. This has led to increasing interest in combined anteversion (CA), which incorporates both acetabular and femoral components [2,3,5].

 

Studies have demonstrated that CA is a better predictor of impingement and dislocation than isolated cup positioning [7,13]. Furthermore, spinopelvic mobility has been shown to influence functional orientation of the acetabulum [8,10,11,15].

 

In the Indian population, cultural activities such as squatting and cross-legged sitting place additional biomechanical demands on the hip joint, which are not considered in traditional Western models.

 

AIM

To determine the optimal combined anteversion range in Indian patients undergoing THR and correlate it with functional outcomes.

 

MATERIALS AND METHODS

  1. Study Design

Prospective observational study.

 

  1. Sample Size

82 patients undergoing primary THR.

 

  1. Inclusion Criteria
  • Age >18 years
  • Primary THR (AVN, OA, fracture neck femur)

 

  1. Exclusion Criteria
  • Revision THR
  • Neuromuscular disorders
  • Severe deformities

 

  1. Surgical Technique

All surgeries were performed using standard posterior approach. Component positioning followed conventional guidelines with intraoperative estimation of anteversion [12].

 

  1. Measurement of Anteversion

Acetabular anteversion measured radiographically using standardized methods [4,6,21]. Femoral anteversion assessed intraoperatively and radiologically.

 
   


Combined Anteversion (CA) = cup + stem anteversion

Grouping

Group A: CA <25°

Group B: CA 25–50°

Group C: CA >50°

 

Outcome Measures

Functional Scores

Harris Hip Score (HHS)

WOMAC score

Lifestyle Assessment

Squatting

Cross-legged sitting

 

Complications

Dislocation

Impingement

Limp

 

Statistical Analysis

ANOVA for continuous variables

Chi-square test for categorical variables

p < 0.05 considered significant

RESULTS

Demographics

Mean age: 54.2 ± 12.1 years

AVN most common indication (52%)

 

Table 1: Functional Outcomes by Combined Anteversion

 

Patients in Group B (25–50°) showed significantly higher HHS compared to other groups (p < 0.001). [table 1, figure 1 & 2]

Figure 1: HHS vs Combined Anteversion

Figure 2: WOMAC vs Combined Anteversion

Lifestyle Outcomes [Figure 3]

Squatting ability highest in Group B

Cross-leg sitting significantly better in Group B

Figure 3: Lifestyle Outcomes

 

Complications

Dislocation occurred predominantly in Group A and Group C, consistent with previous literature highlighting the importance of optimal component positioning [14,16,17,20].

 

DISCUSSION

This study demonstrates that combined anteversion significantly influences functional outcomes following THR. Patients within the 25–50° range showed superior outcomes, consistent with previously described combined anteversion concepts [3,5].

 

However, our findings suggest that the optimal range for Indian patients may extend slightly beyond traditional values, supporting the concept of a functional safe zone rather than a fixed radiological target [19].

 

The role of spinopelvic dynamics further complicates the concept of a universal safe zone, as pelvic tilt can alter functional anteversion during daily activities [10,11,15].

 

Additionally, the persistence of dislocations within traditional safe zones highlights the limitations of relying solely on static measurements [9,14,16].

 

Our study uniquely incorporates lifestyle-based functional outcomes, demonstrating that slightly higher anteversion may facilitate activities such as squatting without compromising stability.

 

Limitations

Short follow-up duration

Moderate sample size

Radiographic measurement variability

 

Conclusion

Optimal combined anteversion for Indian patients undergoing THR appears to lie between 30°–55°, offering improved functional outcomes and reduced complications.

This study supports a shift toward patient-specific and function-oriented implant positioning rather than reliance on traditional universal safe zones.

 

REFERENCES

  1. Lewinnek GE, Lewis JL, Tarr R, Compere CL, Zimmerman JR. Dislocations after total hip-replacement arthroplasties. J Bone Joint Surg Am. 1978;60(2):217–220.
  2. Dorr LD, Malik A, Dastane M, Wan Z. Combined anteversion technique for THA. Clin Orthop Relat Res. 2009;467(1):119–127.
  3. Widmer KH, Zurfluh B. Compliant positioning for optimal ROM. J Orthop Res. 2004;22(4):815–821.
  4. Widmer KH. Measurement of acetabular cup anteversion. J Arthroplasty. 2004;19(3):387–390.
  5. Yoshimine F. Safe zones for combined anteversion. J Biomech. 2006;39(7):1315–1323.
  6. Murray DW. Measurement of acetabular orientation. J Bone Joint Surg Br. 1993;75(2):228–232.
  7. Malik A, Maheshwari A, Dorr LD. Impingement in THR. J Bone Joint Surg Am. 2007;89(8):1832–1842.
  8. Lazennec JY, Riwan A, Gravez F, et al. Hip-spine relationships. Hip Int. 2007;17(Suppl 5):S91–104.
  9. Esposito CI, Gladnick BP, Lee YY, et al. Cup position alone does not predict dislocation. J Arthroplasty. 2015;30(1):109–113.
  10. Maratt JD, Esposito CI, McLawhorn AS, et al. Pelvic tilt in THR. J Arthroplasty. 2015;30(3):387–391.
  11. Buckland AJ, Vigdorchik J, Schwab FJ, et al. Spine deformity and acetabular anteversion. J Bone Joint Surg Am. 2015;97(23):1913–1920.
  12. Sendtner E, Müller M, Winkler R, et al. Femur-first concept. Z Orthop Unfall. 2010;148(2):185–190.
  13. Pour AE, Schwarzkopf R, Patel KP, et al. Combined anteversion influence. J Arthroplasty. 2021;36(7):2393–2401.
  14. Jolles BM, Zangger P, Leyvraz PF. Risk factors for dislocation. J Arthroplasty. 2002;17(3):282–288.
  15. McKnight BM, Trasolini NA, Dorr LD. Spinopelvic motion. J Arthroplasty. 2019;34(Suppl):S53–S56.
  16. Rowan FE, Benjamin B, Pietrak JR, Haddad FS. Prevention of dislocation. J Arthroplasty. 2018;33(5):1316–1324.
  17. Callanan MC, Jarrett B, Bragdon CR, et al. Cup malposition risk. Clin Orthop Relat Res. 2011;469(2):319–329.
  18. Learmonth ID, Young C, Rorabeck C. THR: operation of the century. 2007;370:1508–1519.
  19. Tezuka T, Heckmann ND, Bodner RJ, Dorr LD. Functional safe zone. J Arthroplasty. 2019;34(3):S56–S61.
  20. Woo RY, Morrey BF. Dislocations after THR. J Bone Joint Surg Am. 1982;64:1295–1306.
  21. Ackland MK, et al. Measurement of acetabular version. J Biomech. 2011;44:199–205.

 

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