International Journal of Medical and Pharmaceutical Research
2024, Volume-5, Issue-1 doi: 10.5281/zenodo.10633318
Original Article
MRI Evaluation of Covid 19 Associated Rhinoorbital Cerebral Mucormycosis
 ,
Published
Feb. 2, 2024
Abstract

Background and Objective: Parallel opportunistic infections have been identified as an additional illness spectrum since the COVID-19 pandemic began. One of these opportunistic diseases that needs attention is mucormycosis, which has seen a sharp rise in cases and rapid dissemination when compared to the pre- COVID-19 era. Following COVID-19, there have been instances of immune suppression. in addition to the presence of comorbid illnesses, which raises the possibility that mucormycosis will be deadly. Early detection and prompt diagnosis can save lives. Magnetic resonance imaging (MRI) imaging is the cornerstone of care for individuals with ROCM. The use of MRI imaging in ROCM was reviewed in this review, with particular attention paid to the optimal MRI protocol in a ROCM case, the routes by which infection spreads, the conventional diagnostic features, MRI for disease staging, MRI for prognostication, MRI for follow-up, and imaging characteristics of common differentials in ROCM.

Materials and Methods: This hospital-based prospective study was conducted on 20 people who tested positive for COVID-19 RTPCR over the course of six months, from March 2021 to August 2021, at the Department of Radiodiagnosis, Alluri Sitarama Raju Academy of Medical Sciences, Eluru. Patients had PNS, orbits, and brain MRIs, which were then analyzed. The statistical analysis employed descriptive statistics.

Image reconstruction: Volume rendering approaches for all axial, coronal, and sagittal reformats have been applied. For vascular assessment, projection images with the maximum and average intensities are used. As noted, clinical and radiological follow-up was done on the cases.

Results: 20 patients were discovered to have rhino orbital cerebral mucor mycosis out of 50 COVID 19 RTPCR positive cases; follow-up biopsies confirmed this diagnosis. Out of 20 individuals with mucor, 11 patients had involvement in the nasal cavity and paranasal sinuses, 6 patients had orbital involvement, and 4 patients had central nervous system involvement.

Conclusion: Imaging is essential for guiding surgical treatments even before clinical symptoms appear and for assessing the severity of the disease, which facilitates a timely diagnosis. When mucor spreads into the orbits and neck regions early in the disease, fat stranding may be the only imaging indicator of extra-sinus dissemination. Therefore, it is critical to thoroughly assess fat-suppressed sequences on MRI when making a diagnosis.MRI is used as a screening method to assess mucormycosis even in the absence of clinical symptoms. Therefore, MRI is essential for determining the severity, stage, and prognosis of a disease, information that is useful for therapy planning.

Recommended Articles
Loading Image...
Volume-5, Issue-1
Citations
276 Views
379 Downloads
Share this article
License
Copyright (c) International Journal of Medical and Pharmaceutical Research
pdf Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
All papers should be submitted electronically. All submitted manuscripts must be original work that is not under submission at another journal or under consideration for publication in another form, such as a monograph or chapter of a book. Authors of submitted papers are obligated not to submit their paper for publication elsewhere until an editorial decision is rendered on their submission. Further, authors of accepted papers are prohibited from publishing the results in other publications that appear before the paper is published in the Journal unless they receive approval for doing so from the Editor-In-Chief.
IJMPR open access articles are licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. This license lets the audience to give appropriate credit, provide a link to the license, and indicate if changes were made and if they remix, transform, or build upon the material, they must distribute contributions under the same license as the original.
Logo
International Journal of Medical and Pharmaceutical Research
About Us
The International Journal of Medical and Pharmaceutical Research (IJMPR) is an EMBASE (Elsevier)–indexed, open-access journal for high-quality medical, pharmaceutical, and clinical research.
Follow Us
© Copyright IJMPR | All Rights Reserved