Introduction:Intraventricular haemorrhage (IVH) remains a catastrophic neurological complication with considerable mortality and neurodevelopmental disability in preterm neonates.Given that preterm birth is a major cause, many strategies have been put forth for its prevention . The newest on the present day list is Magnesium Sulphate (MgSo4).Aims and Objectives:To determine the effect of exposure of antenatal magnesium sulfate on intraventricular hemorrhage in premature newborns evaluated by cranial ultrasoundand other neonatal complications at birth.Materials and Methods: This prospective interventional study was conducted on 70 women admitted to labor room in the Department of Obstetrics and Gynaecology, Sawai Mansingh Medical College, Jaipur. Women with singleton pregnancy between 28 to 32 weeks gestational age with expected delivery within 24 hours were included. Groups were allocated using flipcoin method into cases and controls, and the treatment group was administered with Magnesium Sulphate. Neonatal complications were reported at birth. On day 7, cranial ultrasound was done to evaluate IVH and its Papile grading.Results: Our study concluded that the occurence of IVH was low in both groups, though there wasslightly higher occurence ofIVH in the group not receiving MgSO4compared to the groupreceiving MgSO4(11.4% vs 2.9%). HIE(22.9% vs 25.7%), RDS (20% vs 25.7%), ROP(0% vs 5.7%), Hydrocephalus (0% vs 5.7%), Neonatal seizures (5.7% vs 8.6%) and Neonatal mortality (8.6% vs 11.4%) were the neonatal outcomes reported among those administered MgSo4 and those not.Conclusion: This study contributes to the body of evidence indicating that prenatal MgSO4 use on a large scale might be advantageousin prevention of IVH in preterm neonates. It offers a great deal of promise to lessen neurocognitive impairment and safeguard the growing fetal brain.