Introduction: Trauma to the upper extremities are very common especially in younger individuals who often sustain these injuries by way of moderate to high-energy mechanisms such as motor vehicle accidents or sports injuries, whereas elderly individuals are more likely to sustain injuries because of the sequela of a low-energy fall ̐[1]. There are numerous conservative treatment options available, the most common being the use of a sling or ’figure-of-eight’ bandage however, Surgical treatment is indicated if mediastinal structures are placed at risk because of fracture displacement, in case of soft-tissue compromise, or when multiple trauma and/or “floating shoulder” injuries are present [2]. In the latter, the common anaesthetic technique for patients is general anesthesia (GA) however Regionalanesthesia (RA) can be a preferred as an alternative to (GA) to avoid complications as well as to provide post operative analgesia. The aim of this study is to determine if Interscalene brachial Plexus block is a safe alternative to general anaesthesia for Clavicle surgeries. Objective: To report a case of Clavicle fracture fixation surgery done under interscalene block solely. Methods: A literature review was conducted using databases such as PubMed, Elsevier, and GoogleScholar to identify relevant studies comparing ISB and GA for clavicle fracture surgeries. Result: We present a case of a 40 year old male with right clavicle fracture following an alleged history of trauma, who underwent ORIF and plating in supine position under Interscalene block. Conclusion: We conclude that Interscalene Block is well tolerated and has favourable outcomes as compared to general anesthesia and can be considered for clavicle fixation surgeries.