International Journal of Medical and Pharmaceutical Research
2026, Volume-7, Issue 2 : 1012-1019
Research Article
Knowledge and Awareness of Diabetes Mellitus and its Complications in Diabetic Patients in Tertiary Care Hospital
 ,
 ,
 ,
Received
Feb. 17, 2026
Accepted
March 8, 2026
Published
March 20, 2026
Abstract

Introduction: Diabetes is one of the largest global health emergencies of this century, ranking among the 10 leading causes of mortality. Diabetes mellitus (DM) is a chronic metabolic disorder marked by hyperglycemia due to impairments in insulin production, insulin function, or both. Despite advances in the diagnosis and treatment of DM, the occurrence of related complications remains significantly high. Aim: This study aims to evaluate diabetic patients’ awareness of complications and how it influences their compliance with treatment. Materials and methods: A cross-sectional study was conducted in Department of Biochemistry in association with Department of General Medicine, NRI Institute of Medical Sciences, Andhra Pradesh, India. This study involved 500 individuals aged over 15 years with type 1 or type 2 diabetes, of both genders, who consented to participate and were selected through convenience sampling. The study lasted 7 months. Using social media sites, a predefined questionnaire was distributed to the patients who came to General Medicine OP. The questionnaire covered all the necessary data. Results: In our study, majority of patients are in age group of ≥ 50 years, 249 (49%) 500 patients. Only 20 (4%) patients are in age group of 18-30 years. 31-50 years of age group were 235 (47%). In this study, majority were females, 310 (62%), indicating the incidence of DM is higher in female. Most of the patients are Illiterate 320 (64%) and 420 (84%) patients are from rural background. Concerned with duration of diabetes, 80 (16%) have DM from 1yr. 175 (35%) have DM from 1-5 yrs.   95 (19%) have DM from 5-10 yrs. 150 (30%) of patients have DM from ≥10yrs. Majority of patients have DM from 1-5 yrs. Concerned with diabetic complications; 210 (42%) patients are aware of complications related to DM. In this study, 280 (56%) were advised to take anti-diabetic medications. Only 20 (4%) patients were advised insulin shots, 110 (22%) patients were advised both antidiabetic drugs and insulin. Out of 500 patients 280 (56%) exercised regularly. Only 140 (28%) DM patients own Glucometer and are conscious of regular monitoring of their blood glucose. In this study, 85 (17%) patients test their blood sugar every week. 45 (9%) patients test in every 2 weeks. 210 (42%) test every 3 weeks. In last month 160 (32%) DM patients have not tested their blood glucose. In this study, 255 (51%) patients demonstrated awareness of the symptoms of hypoglycemia, whereas 245 (49%) reported a lack of awareness. In this, 210 (42%) patients were aware that diabetes mellitus can affect vital organs such as the heart, nervous system, and kidneys. Regarding healthcare-seeking behavior for diabetes management, 415 (83%) patients reported visiting a general physician, 40 (8%) consulted an endocrinologist. When asked about the frequency of medical consultations for diabetes, 170 (34%) patients reported visiting a doctor 5 or more times per year, 95 (19%) visited 3 to 4 times per year. Notably, 125 (25%) patients reported never visiting a doctor for their diabetes. In terms of specialized diabetes care, 85 (17%) patients had visited a diabetes educator. However, the majority 385 (77%) reported not consulting any such health professionals. With respect to self-examination of feet in the past month, 335 (67%) patients reported not examining their feet at all, 145 (29%) examined their feet 1 to 3 times. With regard to eye examinations, 180 (36%) patients had undergone an eye check-up within the past year. Notably, 230 (46%) patients reported never having had their eyes checked. When asked about sexual health, only 5 (1%) patients reported having been treated for or experienced erectile dysfunction/loss of libido. The majority 420 (84%) denied such issues. Conclusion: Our findings underscore substantial gaps in awareness, self‐care, and utilization of specialist/support services among diabetic patients. These gaps likely translate into preventable morbidity. Interventions are urgently required at multiple levels: patient education, healthcare delivery, screening, and systemic support to improve quality of life and reducing healthcare burden. 

Keywords
INTRODUCTION

Diabetes is one of the largest global health emergencies of this century, ranking among the 10 leading causes of mortality.[1] The world prevalence of adult diabetes in 2010 is 285 million and predicted to reach 439 million in 2030 [2].

 

Diabetes mellitus (DM) is a chronic metabolic disorder marked by hyperglycemia due to impairments in insulin production, insulin function, or both. Despite advances in the diagnosis and treatment of DM, the occurrence of related complications remains significantly high [3]. It is increasingly evident that, for most individuals with both type 1 and type 2 diabetes, treating the major complications of the disease is just as essential as combating the current global diabetes epidemic itself [4]. Diabetes mellitus is projected to become a leading cause of morbidity and mortality in the future. The primary goal of DM treatment is to prevent mortality and complications by maintaining normal blood glucose levels. However, even with appropriate treatment, blood glucose levels may remain elevated, potentially leading to complications such as impaired fat metabolism, nerve damage, and eye disorders [5]. Common complications of diabetes affect the kidneys, retina, cardiovascular system, nerves, and liver, there are currently no effective treatments available to reverse the damage to these organs [6].

 

India is home to the world's second highest number of diabetic patients. India has 74.9 million diabetics in 2021 projected to increase to 124.9 million by 2045 [7]. According to IDF, one out of every seven diabetic adults worldwide resides in India, and one in every third household has diabetic patients. There are three worrying trends as far as the epidemiology of diabetes in India is concerned. Firstly, it is now affecting people at a younger age [8]. Secondly, earlier a disease of the affluent, diabetes has now started affecting the middle and even the lower socioeconomic strata [9]. Thirdly, the disease, which was mostly confined to urban areas earlier, is now affecting the rural population as well. This challenging burden of diabetes is a result of different reasons, mainly a rising obesity rate [10].

 

Complications related to diabetes mellitus can be life-threatening. However, these complications can be effectively managed if patients adhere to proper treatment and control measures [11, 12]. Knowledge and awareness through self-management training and diabetes education are crucial for effective diabetes care and management. It is important for individuals with DM to have a thorough understanding of the disease, its risk factors, potential complications, and available treatment options to help reduce the risk of complications [13, 14]. This study aims to evaluate diabetic patients’ awareness of complications and how it influences their compliance with treatment.

 

MATERIALS AND METHODS:

A cross-sectional study was conducted in Department of Biochemistry in association with Department of General Medicine, NRI Institute of Medical Sciences, Visakhapatnam, Andhra Pradesh, India. This study has been approved by the institutional ethics committee and informed consent was obtained from the study participants. This study involved 500 individuals aged over 15 years with type 1 or type 2 diabetes, of both genders, who consented to participate and were selected through convenience sampling. The study lasted 7 months. Using social media sites, a questionnaire was distributed to the patients who came to General Medicine OP. The questionnaire covered the following data: patients’ socio-demographic characteristics like age, gender, education, occupation. The second section covered the parameters related to clinical characteristics of participants like the type of diabetes, duration of diabetes, in addition to, the management of blood sugar level. The third one covered participants’ awareness toward diabetic complications such as retinopathy, renal failure and neuropathy. There was no risk to the participants because it was a descriptive study that helped to determine the awareness of diabetic complications

 

RESULTS:

The present study was conducted to evaluate diabetic patients’ awareness of complications and how it influences their compliance with treatment. In our study, majority of patients are in age group of ≥ 50 years, 249 (49%) 500 patients. Only 20 (4%) patients are in age group of 18-30 years. 31-50 years of age group were 235 (47%). In this study, majority were females, 310 (62%), indicating the incidence of DM is higher in female compared to males. In our study, most of the patients are Illiterate 320 (64%) and 420 (84%) patients are from rural background. Concerned with duration of diabetes, 80 (16%) have DM from 1yr. 175 (35%) have DM from 1-5 yrs.   95 (19%) have DM from 5-10 yrs. 150 (30%) of patients have DM from ≥10yrs. In our study, majority of patients have DM from 1-5 yrs as shown in table 1.

 

Table 1: Sociodemographic data of Diabetic patients in Tertiary care Hospital.

Sociodemographic data

Number

Percentage

Age in years

18-30

20

4

31-50

235

47

>50

245

49

Gender

Male

190

38

Female

310

62

Education level

Literate

180

36

Illiterate

320

64

Residence

Rural

420

84

Urban

80

16

Duration of Diabetes

≤1yr

80

16

1-5yr

175

35

5-10yr

95

19

>10yrs

150

30

 

Concerned with diabetic complications, 210 (42%) patients are aware of complications related to DM. out of 210, urban area is 40 (8%) and rural area is 170 (34%), indicating rural patients are well aware of diabetic complications compared to urban patients. In this, majority of them were Illiterate 115 (23%) and literate were 95 (19%). Females were more 145 (29%) compared to men 65 (13%) as shown in Table 2.

 

Table 2 Distribution of patients who are aware of Diabetic complications.

Parameters

Number

Percentage

Total patients aware of complications

210

42

  1. Urban

40

8

  1. Rural

170

34

Literate

95

19

Illiterate

115

23

male

65

13

Female

145

29

 

In this study, 280 (56%) were advised to take anti-diabetic medications. Only 20 (4%) patients were advised insulin shots, May be due to their non responsiveness to anti-diabetic drugs. 110 (22%) patients were advised both antidiabetic drugs and insulin. 90 (18%) patients were not given any medication immediately on diagnosis. Maybe they must have been advised lifestyle changes or might be taking ayurvedic or Homeopathic drugs.

 

Out of 500 patients 280 (56%) exercised regularly. This shows that majority of patients are aware that exercise in any form like walking, Gym increases their glucose tolerance. Only 140 (28%) DM patients own Glucometer and are conscious of regular monitoring of their blood glucose. Rest 360 (72%) do not have glucometer. This implies that patients in study group are not tech savvy. In this study, 85 (17%) patients test their blood sugar every week. 45 (9%) patients test in every 2 weeks. 210 (42%) test every 3 weeks. In last month 160 (32%) DM patients have not tested their blood glucose. This implies educational programmes should be conducted to create a sense of awareness among DM patients.

 

In this study, 255 (51%) patients demonstrated awareness of the symptoms of hypoglycemia, whereas 245 (49%) reported a lack of awareness. This indicates that nearly half of the patients are unable to recognize hypoglycemic symptoms, highlighting a potential gap in patient education and self-management. In this, 210 (42%) patients were aware that diabetes mellitus can affect vital organs such as the heart, nervous system, and kidneys, while 290 (58%) patients were unaware of these complications. 115 (23%) patients were checked for lipid profile and 385 (77%) were not.

 

Regarding healthcare-seeking behavior for diabetes management, 415 (83%) patients reported visiting a general physician, 40 (8%) consulted an endocrinologist, 30 (6%) sought care from a registered medical practitioner (RMP), and 15 (3%) preferred alternative systems of medicine. When asked about the frequency of medical consultations for diabetes, 170 (34%) patients reported visiting a doctor 5 or more times per year, 95 (19%) visited 3 to 4 times per year, and another 95 (19%) reported 1 to 2 visits per year. A smaller proportion consulted less frequently, with 5(1%) visiting once every 2–3 years and 10 (2%) once every 5 years. Notably, 125 (25%) patients reported never visiting a doctor for their diabetes.

 

In terms of specialized diabetes care, 85 (17%) patients had visited a diabetes educator and 30 (6%) had consulted a dietician in the past 12 months. However, the majority 385 (77%) reported not consulting any such health professionals. With respect to self-examination of feet in the past month, 335 (67%) patients reported not examining their feet at all, 145 (29%) examined their feet 1 to 3 times, and only 20 (4%) examined their feet 4 or more times. With regard to eye examinations, 180 (36%) patients had undergone an eye check-up within the past year, 25 (5%) within 1–2 years, 30 (6%) within 2–5 years, 15 (3%) within 5–10 years, and 20 (4%) more than 10 years ago. Notably, 230 (46%) patients reported never having had their eyes checked. When asked about sexual health, only 5 (1%) patients reported having been treated for or experienced erectile dysfunction/loss of libido. The majority 420 (84%) denied such issues, while 75 (15%) were unsure or did not know as shown in table 3.

 

Table 3: Overview of awareness of DM and remedial measures taken by our study subjects.

Parameters

Number

Percentage

Q1. When your diabetes was diagnosed, what advice and /or treatment were you given?

a.    Oral antidiabetic drug

280

56

b.   Insulin

20

4

c.    Both (a+b)

110

22

d.   None

90

18

Q2. Do you exercise regularly

  1. Yes

280

56

  1. No

220

44

Q3. Do you own a Glucometer

  1. Yes

140

28

  1. No

360

72

Q4. How often have you tested your sugar levels in the last month

  1. >1 every week  

85

17

  1. >1 in two weeks  

45

9

  1. >1 in 3 weeks  

210

42

  1. None

160

32

Q5. Do you know the symptoms of Hypoglycemia? (Diaphoresis, palpitation, tremor, headache, malaise)

  1. Yes

255

51

  1. No

245

49

Q6. Are you aware that Diabetes can affect your heart, kidneys, and nervous system

  1. Yes

210

42

  1. No

290

58

Q7. Have you ever checked your lipid profile?

  1. Yes

115

23

  1. No

385

77

Q8. What type of doctor looks after your diabetes?

  1. General Physician     

415

83

  1. Endocrinologist

40

8

  1. RMP

30

6

  1. Alternative medicine

15

3

Q9. Approximately how often do you visit a doctor for your diabetes?

a.       5 or more times a year  

170

34

b.       3 to 4 times a year

95

19

c.        1 to 2times a year

95

19

d.       Once every 2 or 3 years

5

1

e.       Once every 5 years  

10

2

f.        Never

125

25

Q10. Within the past 12 months have you visited any of these health professionals?

  1. Diabetes educator

85

17

  1. Dietician

30

6

  1. None

385

77

Q11. How often have you examined your feet in the last month

  1. None

335

67

  1. 1 to 3 times

145

29

  1. 4 or more times

20

4

Q12. How long has it been since you last had your eyes checked?

  1. Within 1-year    

180

36

  1. 1 to 2 Years     

25

5

  1. 2 to 5 Years    

30

6

  1. 5 to 10 Years    

15

3

  1. >10 years

20

4

  1. None

230

46

Q13. Have you ever been treated for or suffered from erectile dysfunction/Loss of libido?

  1. Yes

5

1

  1. No

420

84

  1. Don’t know

75

15

 

Figure 1 shows the percentage of Diabetic patients aware and unaware of complications in form of pie chart. Majority of patients 58% are unaware of complications. This stresses the need for educational programmes for not only patients but also first-hand health care professional.

   

Figure 1: Awareness of Diabetic patients to complications.

 

DISCUSSION

DM can lead to various complications that affect multiple systems throughout the body. Among the most significant and chronic complications associated with DM are conditions such include coronary artery disease, nephropathy, diabetic neuropathy and retinopathy. Awareness of complications can lead to their prevention thereby reducing morbidity and mortality

 

This study reveals several important gaps in knowledge, health‐seeking behaviors, and self‐care practices among people with diabetes. The following discussion integrates our findings with existing literature, to contextualize them and suggest ways for.

 

In our study majority of DM patients are above 50yrs of age. This suggests that Type II DM is more common in study. In a study done by Esmaeel et al., reported that age distribution reveals a predominantly older demographic, with 145 (37.7%) of participants over 40 years old (15).

 

Females have higher incidence of DM compared to males. This is consistent with a study done by Asiedu, C, et al., reported that majority were female, comprising 74.1%  [16].

 

Awareness of hypoglycemia and diabetic complications

In our study, approximately 51% of patients were aware of hypoglycemia symptoms, and 42% knew that diabetes can affect organs like the heart, nervous system, and kidneys. These rates suggest that nearly half of patients remain uninformed about critical aspects of their condition.

 

In a study by Alrasheedi AA et al., reported that about Regarding knowledge of hypoglycemia as a complication of DM, 326 (88.59%) participants were aware of it. The gap in knowledge about complications is echoed in many studies: for example, many patients know some complications (e.g. blindness, kidney failure) but are less aware of others [17].

 

Thus, while your awareness figures are concerning, they are somewhat lower than in some comparable Indian settings (for hypoglycemia at least), indicating room for improvement.

 

Healthcare‐seeking behavior and provider access

You found that 83% see general physicians, 8% see endocrinologists, 6% see RMPs, and 3% use alternative medicine. Moreover, over a quarter (25%) of respondents never visited a doctor for their diabetes.

 

  • This aligns with studies showing that access to specialists is limited for many diabetic patients, especially in low‐resource or rural settings.
  • The large percentage not visiting clinicians is troubling, and supports findings from studies showing delays or omissions in seeking care, which increase risk of complications.

 

Utilization of specialist health professionals (educators, dieticians)

Only 17% had visited a diabetes educator, 6% a dietician in the last 12 months, while 77% had seen neither.

  • This is consistent with literature from India (and elsewhere) showing that structured diabetes education and nutritional counselling is underutilized. Studies show that such professional input (education, diet advice) leads to better glycemic control and complication prevention.

 

Self‐care practices: Foot examination & Eye examinations

  • Foot self‐examination: 67% of your patients examined their feet not at all in the past month; only 4% did so four or more times.
  • Eye exams: In your study, 36% had an eye exam within 1 year, but a large proportion (46%) never had their eyes checked.
  • This finding is concerning, given that diabetic retinopathy can be asymptomatic in early stages. Literature advocates for annual screening for retinopathy for people with diabetes.

 

Sexual health

Only 1% reported erectile dysfunction or loss of libido; 15% were unsure.

  • This low reporting might reflect under‐reporting due to stigma, lack of awareness that sexual dysfunction is a complication of diabetes, or poor probing in healthcare encounters. Literature has shown that sexual dysfunction is relatively common in diabetics but often underrecognized.

 

Implications

  • The substantial proportion of patients unaware of hypoglycemia symptoms, diabetic complications, and the importance of foot/eye care suggests that current patient education is insufficient.
  • The low use of specialists such as educators and dieticians points to gaps in multidisciplinary care. This is problematic because nutritional counselling and education are known to be essential in diabetes self‐management.
  • Poor self‐care practices (foot checks, eye exams) raise risk for preventable complications—ulcers, amputations, vision loss.
  • The healthcare system may need to focus on improving access, reducing barriers (cost, awareness, stigma), and integrating regular screening into routine diabetes follow‐ups.

 

Strengths

  • Our study covers multiple domains: awareness, health‐seeking, self‐care, sexual health. That gives a comprehensive view of patient behaviors and knowledge.
  • Use of quantitative data allows for drawing clear proportions, which can facilitate targeted intervention planning.

 

Limitations

  • Self‐report bias: Patients may over‐ or under‐report behaviors (e.g., visits, self‐exams).
  • Cross‐sectional design: we cannot determine causality (e.g., whether knowledge leads to better self‐care, or whether those who are engaged in care learn more).
  • Possible selection bias: if your sample is from clinics or those willing to participate, maybe people already more engaged in care are over‐represented (or conversely).
  • Underreporting of sensitive issues: sexuality, erectile dysfunction may be under‐reported due to social desirability or embarrassment.

 

Ethical clearance has been granted for this study.

 

Conflict of interest: There is no conflict of interest.

 

Recommendations for Practice and Policy

  1. Enhanced patient education programs
  • Integrate structured education on hypoglycemia, complications (especially heart, kidney, neurological) frequently, using culturally appropriate materials, and target both patients and families.
  • Use group sessions, peer support, and regular refreshers.
  1. Strengthen roles of diabetes educators, dieticians
  • Make access to these professionals more routine in diabetes clinics.
  • Possibly subsidize or include such services in primary care settings.
  1. Regular screening protocols
  • Implement systems to ensure annual examinations: feet (self and by clinician), eyes (retinopathy screening), possibly kidney/neurovascular screening.
  • Use reminders, checklists, or electronic health record alerts.
  1. Address barriers
  • Identify cost, transport, literacy, stigma, or cultural concerns that prevent patients from seeking care or reporting issues (e.g., sexual dysfunction).
  • Consider mobile clinics or tele‐medicine for rural/underserved populations.
  1. Future research
  • Qualitative studies exploring why patients do not visit doctors, or why awareness is low (especially around complications).
  • Intervention studies: measuring the effect of education, reminders, access improvements, etc., on improving self‐care and outcomes.
  • Larger, possibly longitudinal studies to assess causal links (e.g., does increased awareness lead to fewer complications?).

 

CONCLUSION

Our findings underscore substantial gaps in awareness, self‐care, and utilization of specialist/support services among diabetic patients. These gaps likely translate into preventable morbidity (foot ulcers, vision loss, cardiovascular complications). Interventions are urgently required at multiple levels: patient education, healthcare delivery, screening, and systemic support. With targeted efforts, many of the risks identified could be mitigated, improving quality of life and reducing healthcare burden.

 

REFERENCES

  1. International Diabetes Federation. IDF Diabetes Atlas. 9th ed. Brussels, Belgium: International Diabetes Federation; 2019. 
  2. E. Shaw, R.A. Sicree, P.Z. Zimmet Global estimates of the prevalence of diabetes for 2010 and 2030 Diabetes Res. Clin. Pract.2010; 87:4-14.
  3. Iradukunda, Angelique, et al. Diabetic complications and associated factors: A 5-year facility-based retrospective study at a tertiary hospital in Rwanda. Diabetes Metabolic Syndrome and Obesity: Targets and Therapy. 2021;14:4801-4810.
  4. Forbes, Josephine M. and Mark E. Cooper. “Mechanisms of diabetic complications.” Physiological Reviews. 2013;93(1):137-188.
  5. Jin, Qiao and Ronald Ching Wan Ma. Metabolomics in diabetes and diabetic complications: Insights from epidemiological studies.” Cells. 2021;10(11):
  6. Demir, Sevgican, et al. Emerging targets in type 2 diabetes and diabetic complications. Advanced Science. 2021;8(18).
  7. Federation, I. D. IDF Diabetes Atlas 10th Preprint at (2021).
  8. Mohan V, Pradeepa R. Epidemiology of diabetes in different regions of India. Health Administrator. 2009; 22: 1-18.
  9. Mohan V, Ramachandran A, Snehalatha C, et al. High prevalence of maturity-onset diabetes of the young (MODY) among Indians. Diabetes Care. 1985; 8: 371.
  10. Kearns K, Dee A, Fitzgerald AP, Doherty E, Perry IJ. Chronic disease burden associated with overweight and obesity in Ireland: The effects of a small BMI reduction at population level. BMC Public Health. 2014;14:143.
  11. Susan van D, Beulens JW, van der S YT, Grobbee DE, Nealb B. The global burden of diabetes and its complications:An emerging pandemic. Eur J Cardiovasc Prev Rehabil. 2010;17(Suppl 1):S3-8.
  12. Cannon A, Handelsman Y, Heile M, Shannon M. Burden of illness in type 2 diabetes mellitus. J Manag Care Specialty Pharm. 2018;24(9-a Suppl):S5-13.
  13. Alomar MJ, Al-Ansari KR, Hassan NA. Comparison of awareness of diabetes mellitus type II with treatment's outcome in term of direct cost in a hospital in Saudi Arabia. World J Diabetes. 2019;10:463-472.
  14. Amoo T, Green BO, Raghupathi V. The awareness of diabetes, its complications, and preventive measures in a developing country. Int J Health C Management. 2014;7:247-50. 
  15. Esmaeel SE, Alsel BA, Alrawili NF, Alobidan RK, Barghash FN, Alanezi HH, A. Alharbi AD, A Alharbi TD. Awareness of Diabetes Complications among Diabetes Patients in Northern Border Region in Saudi Arabia. Journal of Pioneering Medical Sciences. 2024;13(7):6-14.
  16. Asiedu, C., Owusu-Berning, E. & Erzuah, I.A. Knowledge of diabetes mellitus complication prevention among patients in the central region of Ghana. BMC Endocr Disord. 2024; 24, 209.
  17. Alrasheedi AA, Alqesair MH, Aljurbua HF, Alfanoud GA, Almakrami MH, J Mohammad JE. Knowledge of Complications of Diabetes Mellitus Among Patients Visiting the Diabetes Clinics: A Cross-Sectional Study in the Qassim Region. Cureus. 2023;15(12):e49896. 
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