Introduction: Pharmacovigilance (PV) encompasses the science and activities related to detecting, assessing, understanding, and preventing adverse effects or other drug-related issues. Under-reporting of adverse drug reactions (ADRs) often stems from inadequate knowledge and awareness of Pharmacovigilance. This study evaluates the effectiveness of an educational intervention regarding Pharmacovigilance on knowledge, attitudes, and practices (KAP) among homeopathic practitioners and nursing students.

Objectives: To compare and evaluate the impact of educational intervention in the form of a Pharmacovigilance workshop on the knowledge, attitude and practice regarding Pharmacovigilance (PV) among homeopathic practitioners versus nursing students in a tertiary care teaching hospital.

Methodology: This prospective, cross-sectional, interventional study was carried out following approval from Institutional Ethics Committee which involved 186 participants (93 homeopathic practitioners and 93 nursing students) at a tertiary care hospital. A pre-validated questionnaire was administered before and after a 4-hour Pharmacovigilance workshop.

Results: The study revealed significant improvements in knowledge and attitude on Pharmacovigilance post-intervention, particularly among nursing students. Key findings included increased awareness of Pharmacovigilance, understanding of ADRs versus adverse drug events, and knowledge of India's ADR monitoring system. Nursing students showed greater improvement in recognizing ADR reporting as a professional duty and in practical reporting aspects. Homeopaths demonstrated a notable shift in attitudes towards their role in ADR reporting.

Conclusion: The study found statistically significant improvements in PV knowledge, attitudes, and practices among both groups, with nursing students showing more pronounced improvements. The educational intervention effectively enhanced understanding and engagement with Pharmacovigilance principles among participants.