Golden ‘Reverse S Sign’ – A Reliable Sign of Lung Cancer: A Case Report

doi:10.5281/zenodo.16459279

International Journal of Medical and Pharmaceutical Research

2025, Volume-6, Issue-4 : 167-169 doi: 10.5281/zenodo.16459279

Case Report

Golden ‘Reverse S Sign’ – A Reliable Sign of Lung Cancer: A Case Report

Harshavardhana M

B. Vidyasagar

Siri B.S

Pranav Pisharody

DOI : 10.5281/zenodo.16459279

Published

July 26, 2025

Abstract

Introduction: The "Golden S Sign" is a classic radiologic indicator of bronchogenic carcinoma, especially when involving the right upper lobe bronchus. Early recognition of such signs can prompt further investigation and diagnosis of lung malignancy.

Case Presentation: A 65-year-old male chronic smoker presented with hemoptysis, breathlessness, chest pain, fever, and weight loss. Chest X-ray revealed right upper lobe collapse and hilar prominence. CT scan and bronchoscopy confirmed the presence of a necrotic mass obstructing the right upper lobe bronchus. Histopathological analysis revealed poorly differentiated non-small cell carcinoma.

Conclusion: Despite initial CT-guided biopsy being inconclusive, radiological suspicion guided further diagnostic steps, confirming malignancy. This case highlights the importance of the "Golden S Sign" as a reliable early radiologic clue for lung cancer.

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