International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-5 doi: 10.5281/zenodo.10032837
Original Article
Evaluation of Tropical Acute Kidney Injury and Its Early and Late Outcome in Atertiary Care Hospital in Eastern India
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Published
Oct. 23, 2023
Abstract

Background : Acute kidney injury (AKI) in tropical and subtropical countries differ from their temperate counterparts in their modes of origin and clinical presentation. The aetiology of tropical AKI is varied and the volume of literature on this issue is meagre in eastern part of India .The current study explored the prevalence of different causes of tropical AKI, along with its early and late outcomes  among patients admitted to a tertiary care hospital in Kolkata of Eastern India.

Methods : This is an observational study with prospective nature, conducted in the inpatient wards of a tertiary care teaching hospital in Kolkata at the eastern part of India for a duration of one and half year from February 2020 to July 2021. A sample of 50adult population, aged between 18-90 years comprising both male and female presenting with acute kidney injury undergone the current study.

Results : The mean age of the patients was 30.86 ( with standard deviation+/- 6.56 ) years, most were men, hailing from rural areas. Majority developed AKI following an infection, commonly Malaria and Scrub typhus. Of the non-infectious causes snake bite envenomation was important. Oliguria were the most important complications and 32% patients required haemodialysis. The mean duration of hospital stay was 15.18 (SD +/- 6.64)days. Among the study population8% died when undergoing inpatient treatment in hospital.

Conclusion: Tropical AKI in eastern region of India was mostly caused by infections of which Malaria and Scrub Typhus are common followed  by snakebite envenomation among rural young men. The disease is associated with a long hospital stay but relatively less mortality.

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