Introduction: Ankle fractures are common orthopedic injury. These fractures involve medial and lateral malleolus with sometimes posterior malleolus. Ankle fracture may range from low energy injuries with little or no displacement to complex fractures with significant associated injuries. Stability of these injuries depends on a combination of boney and associated ligamentous injuries. Objective: To assess the evaluation of outcome of surgical management of ankle fracture (medial malleolus) by single swiss malleolar screw. Methods: This prospective study was conducted in Dept. of Orthopaedic and Trauma Surgery, Shaheed Moman Ali Medical College, Dhaka, Bangladesh from January to June-2022. Total 20 patients with malleolar ankle fractures were studied. All of these patients came to ER with acute injuries following RTA, fall from height etc. All of these patients were assessed pre and post operatively. All of these cases were classified according to Lauge-Hansen, Dennis-weber, AO classification. Results: In this series 20 patients with malleolar ankle fractures were studied. Of these, 3 in the operative and 1 in the conservative group were excluded as they were lost for follow up or refused treatment. Of the 20 cases included in this study 5 (25%) cases were treated conservatively and 15(75%) cases by operative methods. Age, sex distribution and side involved. The average age for the whole group was 56.45 years, (25-88 yrs). In this study right side was affected in 9 cases and left side in 11 cases. Maximum study patient were injured from RTA. All of them were treated by minimally invasive technique. Patients were kept on follow up at regular interval. All of the patient’s plasters were removed at around after 28th POD. On consequent follow up patients could dorsiflex and planterflex ankle and walk after brief period of physiotherapy and active exercise. Conclusion: In our study internal fixation by minimally invasive procedure through single swiss malleolar screw for medial malleolus resulted in comparative positive outcome in five patients suffering from ankle fracture.