Evaluation of Effect of Platelet Rich Plasma and Human Umbilical Cord Blood as Topical Application on Chronic Wound

doi:10.5281/zenodo.8089768

International Journal of Medical and Pharmaceutical Research

2023, Volume-4, Issue-3 doi: 10.5281/zenodo.8089768

Original Article

Evaluation of Effect of Platelet Rich Plasma and Human Umbilical Cord Blood as Topical Application on Chronic Wound

Dr. Gourav Kanch

Dr. Mukesh Singh Narwaria

Dr. Ankit Sahu

Dr. Achala Sahai Sharma

DOI : 10.5281/zenodo.8089768

Published

June 28, 2023

Abstract

Background: Platelet rich plasma (PRP) and human umbilical cord blood (HUCB) are two cheap and easily accessible newer modalities used to improve wound healing. The aim of our study is to analyze the effect of these two new modalities and compare it with conventional dressings.

Method: Patients with chronic wounds were divided randomly into three different groups. Group A received a topical application of PRP to their wounds; group B received a topical application of HUCB, while group C were treated with conventional dressings. Wounds were observed weekly and results analyzed at the end of 6 weeks.

Results: Significantly better improvement in wound healing was observed in group A (PRP) and group B (HUCB) patients as compared to group C (Conventional dressing) with a reduction in surface area, improvement in the wound bed, reduction in exudates amount and healthy granulation.

Conclusion: Both PRP and HUCB are cost effective, easy to extract and prepare, and are better and convincing agents used in chronic wounds.

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