International Journal of Medical and Pharmaceutical Research
2024, Volume-5, Issue-1 doi: 10.5281/zenodo.10804306
Original Article
Efficacy of Ketamine as Sole Anaesthetic Agent in Maintaining Perioperative Analgesia and Intraoperative Hemodynamics During Various Short Surgeries at a District Hospitals in Assam: A Prospective, Observational Study
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Published
Feb. 29, 2024
Abstract

Background: ketamine is unique in the sense that it produces dissociative anaesthesia rather than generalized depression of the CNS.  Aim: The aim of this study was to evaluate the effect of administration of ketamine as the only anesthetic drug utilized to induce the patients, maintain intraoperative hemodynamics, postoperative analgesia, and analgesia during certain operations like appendectomy, Hernia, Hydrocele and circumcision at a district hospital in Assam. Settings and Design: This prospective, observational study was conducted from January2023 to December2023, over a period of 12 months in a District hospital in Assam. Materials and Methods: Fifty individuals aged 15 to 40 who were scheduled for various procedures were enlisted. Before surgery, ketamine was administered at a dose of2 to 3 mg/kg. During the procedure, this dose was repeated every ten to fifteen minutes at a rate of .5 to 1 mg/kg. For the first five hours, hemodynamic parameters, the duration until the first rescue analgesia, and complications were noted.  Results: Within the first five hours following surgery, 90% of the patients did not require any postoperative rescue analgesics. 10% of the patients experienced mild postoperative problems, and none of the patients reported pain right away after finishing of procedure.  Conclusion: Ketamine with inducing doses have been shown to be effective analgesics, especially during procedures like conventional appendicectomy, operations for Hernia, Hydrocele and Circumcisions.

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