Background: Metabolic syndrome is a cluster of risk factors associated with increased cardiovascular morbidity and mortality. Left ventricular diastolic dysfunction (LVDD) is an early manifestation of metabolic disease-related cardiomyopathy. This study aimed to investigate the association between metabolic syndrome and LVDD, as well as potential sex differences and specific risk factors. Methods: A cross-sectional study was conducted, including [insert number] participants with metabolic syndrome. Demographic data, clinical measurements, and echocardiographic findings were recorded. Statistical analysis was performed to assess associations and correlations. Results: Among the study population, [insert percentage] % were found to have LVDD. Metabolic syndrome showed a dose-dependent association with the risk of LVDD, with a stronger association observed in men compared to women. Waist circumference and triglyceride levels were identified as independent risk factors for LVDD in men. However, no significant correlations were found between LVDD and blood pressure, fasting blood sugar, waist measurement, triglycerides, or high-density lipoprotein levels. Conclusion: This study provides evidence of an association between metabolic syndrome and the risk of LVDD, emphasizing the importance of early detection to prevent disease progression and cardiac failure. Sex differences were observed, with men showing a stronger association between metabolic syndrome and LVDD. Waist circumference and triglyceride levels were identified as significant risk factors for LVDD in men. These findings highlight the need for comprehensive risk assessment and targeted interventions in individuals with metabolic syndrome to mitigate the risk of LVDD.