Introduction: The imperative to address the high mortality rates associated with coronavirus disease (COVID-19) prompted a swift development of vaccines. By 2021, multiple vaccines had been introduced. However, a lack of conclusive long-term evidence regarding their effectiveness, coupled with apprehensions about potential effects on pregnancy, contributed to a diverse public reaction.Aim: To assess the perception of pregnant and postpartum/ postnatal women with respect to the COVID19 vaccine.Materials and Methods: A cross-sectional study was conducted among antenatal and postnatal mothers at a tertiary healthcare center, with data collection initiated only upon securing consent from study participants. The study, determining a sample size of 373, administered a 33-item questionnaire to the selected participants. Subsequently, the collected data underwent analysis utilizing SPSS software version 24.0.Results: The majority of participants in the study fell within the 28-32 age group (41.9%). When evaluating participant concern levels, 34.6% expressed moderate concern, with a notable association among those with college-level education. Notably, individuals testing positive for COVID-19 and those with COVID-19-positive family members displayed reduced likelihood of vaccine hesitancy. Concerns regarding the safety of COVID-19 vaccines emerged as a significant predictor of vaccine hesitancy. Moreover, participants exhibiting an enhanced sense of safety post-vaccination demonstrated a positive correlation with vaccine acceptance. Conclusion: COVID-19 vaccination acceptance remains suboptimal, with variations observed across demographic variables such as age, location, income, and occupation. Utilizing news and social media platforms can serve as effective tools to