Background: The correlation between hypotension and acute kidney damage in an intensive care unit context is not entirely understood, despite the fact that the relationship between low blood pressure and kidney function has been thoroughly documented in an experimental setting based on evidence from animals. Based on the MIMIC II database, the current study is to estimate the risk of acute kidney injury (AKI) development in intensive care unit (ICU) patients as a function of both the severity of hypotension and the duration of hypotension.Methods: This is a retrospective comparative study performed in 100 patients admitted in ICU of a tertiary care hospital affiliated with a medical college. The study included all patients admitted in ICU from April 2023 to April 2024 with a myriad of aetiologies. The case records were extracted from the ICU records, and details of demographics, aetiology, intervention, ICU stay, days on ventilator and vitals during ICU stay, amongst other parameters, were recorded in a semistructured pro forma. Results:Mean duration of the hypotension was found to be 5.92 hours in the AKI group, while in the non-AKI group it was 4.32 hours. Mean arterial blood pressure of the AKI group was significantly lower than the non-AKI group (p = 0.0031).Conclusion: Our study indicates that the severity and duration of hypotension are both significant risk factors in AKI development in critically ill patient.