International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-3 doi: 10.5281/zenodo.8006769
Original Article
Correlation of Duration and Severity of Disease in Covid19 with CT Thorax Severity Score
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Published
June 5, 2023
Abstract
Background: This study aimed to evaluate the correlation between the CT thorax severity score, duration, and clinical severity in patients with COVID-19. Methods: This retrospective cross-sectional study included 100 patients with COVID-19. The patients were selected based on the inclusion and exclusion criteria. CT thorax severity score, duration of illness, and clinical severity were recorded from the available clinical database. The data was analyzed using statistical tools to evaluate the correlation between the variables. Results: The mean age of the patients was 42.5 years with a standard deviation of 11.8 years. The majority of the patients were male (55%) and had comorbidities such as hypertension (25%) and diabetes (15%). The distribution of CT thorax severity scores showed that 20% of the patients had a score between 0-5, 30% had a score between 6-10, 25% had a score between 11-15, and 25% had a score greater than 15. The duration of illness was less than 7 days in 20% of the patients, between 7-14 days in 40% of the patients, and greater than 14 days in 30% of the patients. The clinical severity of the disease was mild in 20% of the patients, moderate in 40% of the patients, severe in 30% of the patients, and critical in 10% of the patients. A positive correlation was observed between the CT thorax severity score with duration and severity of the disease, with an r2 value of 0.071 and p<0.05. However, a negative correlation was observed between the room air saturation and the CT thorax score, with an R2 value of 0.200 and p<0.05. Conclusion: This study highlights the importance of CT thorax in assessing the severity of illness in patients with COVID-19. The study findings suggest that CT thorax should be performed early in the course of the disease since the average score in patients with mild illness was moderate, indicating lung involvement. The correlation between the CT thorax severity score with duration and severity of the disease highlights the need for regular follow-up of patients with COVID-19 to monitor disease progression.
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