Introduction: In the light of advancements made in the scientific field, the phytotherapy has received an incredible interest because of their low toxicity, pharmacological activities, and economic viability. Among compounds of natural origin, biological activities have been shown by essential oils from aromatic and medicinal plants and have received specific consideration because of their radical-scavenging properties. Therefore, numerous EOs and Probiotics should be considered as a potential anti-Candida agent, for the treatment of Candida species.

Materials and Methods: Swab samples from 50 subjects with Early childhood caries, oral candidiasis and from removable dentures or orthodontic appliances were aseptically collected andsent for microbiological analysis. C. albicans was identified using standard methods. Eight groups were included in the study viz Group I:  Ajwain oil group, Group II: Cinnamon oil group, Group III: Lemon grass oil group, Group IV: Oregano oil group, Group V:  Oil blend group, Group VI: Probiotic group, Group VII: Clotrimazole group and Group VIII: CHX (Chlorhexidine) group. The constituents responsible for the activity of test groups were identified using Gas-Chromatography Mass Spectrometry analysis. The effectiveness of test agents against C. albicans was tested by agar well diffusion method followed by Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC).

Satistical Analysis and Results: The obtained data was calculated using relevant statistical tools such as Students T test and ANOVA. Group II Cinnamon Oil Group was found to be highly effective with mean Zone of Inhibition (ZOI) being 19.83+0.29 mm. The mean MIC for cinnamon oil was 0.625mg/ml and MFC was .33+1.44 mg/ ml that was least concentration effective against C. albicans among all the test groups. There was mean Percentage reduction of colony forming units in all the oils at MIC and MFC with cinnamon being the highest at the lowest concentration.

Conclusion: The results of the present study provided conclusive evidence that Essential oils specifically Cinnamon Oil could be used against Candida present as various source of infections. It could be used for prevention of progression of Early Childhood Caries, as a root canal Irrigant and as a treatment for oral candidiasis and for prevention of the same.