International Journal of Medical and Pharmaceutical Research
2025, Volume-6, Issue-4 : 1-7 doi: 10.5281/zenodo.16417067
Original Article
Community acquired Urinary tract infection isolates and their antibiotic susceptibility pattern
Published
July 17, 2025
Abstract

INTRODUCTION: Urinary tract infection (UTI) is a one of the most common outpatient health problem which is second common diagnosed infection in the community. Management of CA-UTI (Community acquired-urinary tract infection) should be accurate to eliminate the pathogens and to avoid complications, so it is important to do microbiological culture to know the antibiotic susceptibility testing. The aim this study is to know the urinary tract infection pathogens and their susceptibility patterns among patient.

MATERALS AND METHODS: This is a retrospective, cohort study conducted for 6 months on urinary samples collected from the patients presenting with urinary tract infections to outpatient department of our hospital. The data was collected from laboratory culture registers and the results were obtained in the Microsoft Excel and statistically analyzed by calculating the numbers and percentages of all descriptive variables.

RESULTS: Out of 288 urine isolates, 70 (24.3%) were Escherichia coli, 48 (16.6%) isolates were Klebsiella pneumoniae, 40 (13.8%) Pseudomonas aeruginosa isolates, 30 (13.8%) Enterococci isolates, 22 (7.6%), Coagulase Negative Staphylococci isolates, 16 (5.5%), Candida, 10 (3.4%), Proteus spp, 6 (2.08%),  Acinetobacter spp, 4 (1.38%), Citrobacter spp and 2 (0.69%) were Enterobacter spp isolated. Many organisms yielded good sensitivity to penems, nitrofurantoin, fluoroquinolones, cotrimoxazole. Even beta lactam and beta lactamase inhibitor and cephalosporins gave a better sensitivity on testing of few isolates.

CONCLUSION: Neglected Urinary tract infections can lead to serious complications like pyelonephritis, urosepsis. To avoid these complications and to start ultimate antibiotic therapy it is critical to clinicians and microbiologists to focus on various aspects including ordering urine culture, proper sample collection, providing clinical history in requisition forms, and effective utilization of hospital antibiogram.

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