Background: Dengue is a mosquito-borne arboviral disease that has become a global public health challenge, causing epidemics in tropical and sub-tropical countries during the rainy season. This study aimed to assess the clinical profile of dengue infection in children under 12 years of age and to evaluate the outcome of dengue fever.

Methods: The prospective observational study was conducted at Kanyakumari medical college on children with dengue fever admitted from 2020 to 2021. Demographics, clinical profiles, and outcomes of the children with dengue fever were studied. Based on the severity of the disease, children were categorized into three groups; group A has dengue fever. Group B; has dengue fever with warning signs, and group C; has severe dengue.

Results: A total of 63 children were enrolled in the study, with a male predominance (54%) and a highly affected age group of >8 years (65.1%). Fever, vomiting, and abdominal pain were the most common presenting complaints in children. Hepatomegaly was the most common clinical finding .Pleural effusion was reported in 5 children from group B and four children from group C, with significant differences based on the severity of dengue. Most children required 8-10 days of hospitalization, and treatment of antipyretic and intravenous fluids was majorly used. All children recovered from dengue with no mortality.

Conclusion: Early recognition of danger signs clinically and appropriate treatment can reduce mortality and improve patient outcome.