International Journal of Medical and Pharmaceutical Research
2023, Volume-4, Issue-3 doi: 10.5281/zenodo.7976508
Case Report
Chronic Lmphocytic Leukaemia with Pituitary Hypophysitis: A Case Report
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Published
May 27, 2023
Abstract
A 55 years old man came to emergency department of a tertiary care hospital in Kolkata India with complaints of anorexia, weakness and vomiting with no prior history of fever or any significant medical comorbidities. On admission diagnosis was hyponatremia. During hospital stay he was also detected with Type 2 diabetes mellitus. Immunopheno typing (Flow cytometry) findings were consistent with Chronic lymphocytic leukaemia with CD38 expression. CECT whole abdomen and thorax showed features of multiple enlarged lymph nodes. CT Brain (Plain) showed normal study and MRI of pituitary gland showed bulky pituitary gland and infundibulum with homogenous enhancement in post contrast study. With just five examples of pituitary or hypothalamic involvement previously recorded, this case emphasizes an unusual presentation of chronic lymphocytic leukaemia (CLLBinet type A) with pituitary involvement.
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