Assessment of Maternal and Perinatal Outcomes in Pregnancies with Preterm Premature Rupture of Membranes

doi:10.5281/zenodo.14214118

International Journal of Medical and Pharmaceutical Research

2024, Volume-5, Issue-6 doi: 10.5281/zenodo.14214118

Original Research Article

Assessment of Maternal and Perinatal Outcomes in Pregnancies with Preterm Premature Rupture of Membranes

Dr. Vandana N. Kumar Dr. M. Sereesha , Dr. Aparna Nair, Dr. Vishwa Deepthi, G

DOI : 10.5281/zenodo.14214118

Published

Nov. 25, 2024

Abstract

Background: Preterm premature rupture of membranes (PPROM) significantly impacts maternal and perinatal outcomes. This study evaluated outcomes and predictive factors in PPROM cases.Methods: A prospective observational study of 80 women with PPROM between 24 and 36 weeks' gestation was conducted. Maternal and neonatal outcomes were analyzed, and factors affecting latency period were evaluated.Results: The mean gestational age at PPROM was 31.3 ± 3.4 weeks, with a mean latency period of 8.4 ± 4.2 days. Chorioamnionitis occurred in 17.5% of cases. The cesarean section rate was 42.5%, with fetal distress being the primary indication (44.1%). NICU admission was required for 60.0% of neonates, with respiratory distress syndrome affecting 35.0%. Significant correlations were found between latency period and gestational age (r=-0.542, p<0.001), cervical dilatation (r=-0.486, p<0.001), and inflammatory markers (p<0.01). Conclusion: PPROM outcomes are significantly influenced by gestational age and inflammatory markers. Early identification of risk factors may improve management strategies and outcomes.

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