Background: Frozen section helps in rapid intra-operative diagnosis. It is performed to confirm malignancy, to know the organ of origin, to determine adequacy of margins, to detect lymphnode metastasis. Modification of surgery can be decided at the time of surgery on the table on the basis of frozen section findings.

Aims and Objectives: To assess the accuracy of frozen section findings in comparison to gold standard histopathological diagnosis and to find concordance and discordance rate of frozen section with histopathological report.

Methodology: This was a cross-sectional study of 81 frozen section samples done in the department of pathology of a tertiary care hospital from January 2022 to May 2023. All frozen section samples with their permanent tissue samples sent for final histopathological evaluation were included in the study.

Result: A total of 81 speciemens were analyzed, of which 79 specimens diagnosis were concordant and 2 specimens were discordant.

Conclusion: The accuracy of frozen section diagnosis at this tertiary care hospital can be interpretated as comparable with most international quality control statistics for frozen sections. The overall error rate and deferral rates are within the range of previously published studies. The results suggest specific measures should be taken to reduce the number of discrepancies.