A Novel Study of Correlation of Lipid Parameters with Clinical Profile, Staging and Onset of Rhino Orbito Cerebral Mucormycosis in A Covid 19 Pandemic

doi:10.5281/zenodo.8242381

International Journal of Medical and Pharmaceutical Research

2023, Volume-4, Issue-4 doi: 10.5281/zenodo.8242381

Original Article

A Novel Study of Correlation of Lipid Parameters with Clinical Profile, Staging and Onset of Rhino Orbito Cerebral Mucormycosis in A Covid 19 Pandemic

Vijay V

Bhargav V Bhat

Sunil Kumar K

KavyaS T

DOI : 10.5281/zenodo.8242381

Published

Aug. 8, 2023

Abstract

Objectives: Study was undertaken to Estimate the lipid levels in COVID associated mucormycosis (concurrent and post covid) patients ,To correlate the lipid levels with clinical profile and staging of mucormycosis patients and To correlate the lipid levels with onset of covid associated mucormycosis

Methods: One Hundred and Three patients diagnosed with COVID associated Mucormycosis treated in the Hospitals attached to Bangalore Medical College and Research Institute were studied. Information about systemic health condition with lipid profile and other biochemical parameters were collected. Data was analysed. Descriptive statistics including Chi Square test, Mann Whitney U test,Kruskalwallis test, Spearman’s correlation were used and level of significance was kept at 5%. Significance was considered if p<0.5.

Results: The age distribution varied from 22yrs to 75yrs with majority being males(83.4%). Most common symptom among all severity stages was nasal block(79.6%) followed by headache(75.7%). Most Common Comorbidity was DM(50.4%) followed by HTN and DM(36.8%) followed by HTN only (6.7%) followed by DM,HTN and IHD(4.8%) followed by IHD(0.9%).

Conclusion: The study showed a positive correlation between serum lipid profile and stage of Mucormycosis and negative correlation with COVID 19 onset to Mucormycosis onset duration. Hence our hypothesis proved that the patients with altered lipid parameters have higher chances to get severe form of the disease and faster onset of Mucormycosis post COVID 19 and therefore serum lipid profile can be used as a prognostic parameter in predicting the severity and prognosis of COVID 19 associated Mucormycosis.

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