Introduction: The objective is to evaluate efficacy of DWI and MR spectroscopy with conventional MRI in differentiation and grading of brain tumors. Material and Methods: A total number of 60 patients with brain tumours who were referred to Department of Radiodiagnosis, SSIMS&RC, Davanagere over a period of 2 years. Results: Study group consists of 39 male and 21 female patients, majority of the age group is 40.0%. Accordingly, the mean ADC value was 0.81 with a standard deviation of around ±0.216. However, the proportion of each diagnosis was found to be quite different from the actual diagnosis based on HPE, thereby suggesting the possibility of false reports from the DWI procedure. MRS was performed and ratios between choline and creatinine, NAA and creatinine, and choline and NAA to diagnose the condition. Conclusion: On performing both DWI and MRS among patients with history of headache and focal neurological deficits, the study observed the following; DWI was in correlation with ADC values which helped in diagnosing the condition appropriately in most of the cases. MR spectroscopy was successful in imaging and grading the brain tumors using the ratios between choline and creatinine, N-acetyl aspartate and creatinine, and choline and N-acetyl aspartate. MR spectroscopy proven to be more sensitive than diffusion weighted imaging in all the cases.