Herbal Medicines are a fast emerging trend in recent times, as they provide safer, effective and economical treatment to patients. Azadirachta indica (neem) has been an integral part of health and oral care since times immemoral. It has shown to be an effective antimicrobial ant inflammatory and anticancer agent. In india it has been an indespensible part of oral care and is still a popular dental care agent in rural india. Incorporation of neem extract in oral health care products provides a natural solution to oro-dental problems and in maintaining oral health.