Background: Human resources of health care system are vital for its optimal functioning. Nurses occupy 2/3rd of the health work-force with Nurse-population ratio as 1.7/1000 population in India. Though being a part of health care system they themselves are victims to the work stress, occupational hazards and unhealthy life-style resulting in various morbidities.

Objectives: This study aimed to study the socio-demographic profile, estimate the prevalence of morbidities and identify its related factors among the nurses.

Materials & Methods: A cross-sectional study was conducted involving 435 study participants (Universal sampling method) at a tertiary care teaching institute. Data were extracted from the existing medical records.

Results: Out of 435 study participants, 178 (40.9%) were having comorbidities. The prevalent diseases were Hypertension (49.4%), Thyroid disorders (31.5%), Diabetes Mellitus (30.3%), Arthritis (12.9%), Musculoskeletal disorders (11.2%), Bronchial Asthma (7.3%), Dyslipidaemia (3.9%), Cancer (2.8%), Ischaemic heart disease (1.7%) and Lupus disorders (0.6%). 83 (19.1%) needle stick injuries were reported out of which 53(63.9%) were reported and treated. Age (p<0.001), years of service(p<0.001), Shift duties(p<0.001), physical inactivity(p<0.001), Family history of comorbidities(p<0.001) and BMI(p=0.001) showed significant association between the comorbidities.

Conclusion: Hypertension, Thyroid disorders and Diabetes mellitus were the most common comorbidities among the study population. The occupational safety and health of nurses can be improved by regular health check-ups, mental health support, positive working environment, sick leaves and insurance. It will attract future generation to perceive Nursing as a career and thus bridging the Nurse-population ratio gap.