International Journal of
Medical and Pharmaceutical
Research

 Why us?


 Open Access
 Peer-reviewed
 Rapid publication
 Lifetime hosting
 Free indexing service
 Free promotion service
 More citations
 Search engine friendly
A Comparative Study between Injection Nalbuphine and Fentanyl as an Adjuvant to Bupivacaine in Supraclavicular Brachial Plexus Block in Surgeries for Upper Extremity
Dr. Ashwini Kalam, Dr. Gore Prashant, Dr. Prerana Jogdand, Dr. Usha Badole
DOI : 10.5281/zenodo.10807227
Download PDF
Abstract

Background: The efficacy of Nalbuphine and Fentanyl as adjuvants to Bupivacaine in supraclavicular brachial plexus blocks remains a significant point of study in anesthesia, particularly for upper extremity surgeries.

Methods: This randomized study compared Nalbuphine and Fentanyl added to Bupivacaine in 60 patients undergoing upper extremity surgeries. The onset and duration of sensory and motor blocks, as well as hemodynamic parameters, were evaluated.

Results: Nalbuphine demonstrated a significantly faster onset of sensory (5.03 ± 0.88 minutes) and motor blocks (7.1 ± 0.84 minutes) compared to Fentanyl (sensory: 7.5 ± 0.5 minutes, motor: 8.9 ± 0.831 minutes), with p < 0.001. The duration of sensory and motor blocks was also significantly prolonged in the Nalbuphine group (sensory: 360.87 ± 8.64 minutes, motor: 348.17 ± 12.54 minutes) compared to the Fentanyl group (sensory: 344.9 ± 12.24 minutes, motor: 324.1 ± 14.04 minutes), p < 0.001. Hemodynamic parameters were stable and comparable between the groups.

Conclusion: Nalbuphine, as an adjuvant to Bupivacaine, offers a faster onset and longer duration of both sensory and motor blocks in supraclavicular brachial plexus blocks compared to Fentanyl, with maintained hemodynamic stability.

Follow Us


About Us


IJMPR is an international open access source for a high quality and peer reviewed journal in the fields of Medical and Pharmaceutical Sciences. IJMPR publishes research papers across all academic disciplines in the fields of Medical, Pharmaceutical Sciences.

Contact Us


editor@ijmpr.in
Copyright © 2023 | IJMPR | All Rights Reserved

Versicherungsvergleich

A PHP Error was encountered

Severity: Notice

Message: fwrite(): write of 34 bytes failed with errno=122 Disk quota exceeded

Filename: drivers/Session_files_driver.php

Line Number: 267

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/cpanel/php/sessions/ea-php74)

Filename: Unknown

Line Number: 0

Backtrace: