Deep neck space infection leading to Abscess (DNA) are serious diseases that involve several spaces in the neck due to bacterial infections originating from the upper aero digestive tract [1, 4]. Although the incidence of Deep Neck Abscess (DNA) has decreased mainly for the availability of antibiotics, this infection still occurs with considerable frequency in developing countries [2, 3], low socioeconomics [3] group and with comorbidities [3, 4]. A retrospective study of 52 patient with deep neck abscesses caused by multiple etiologiesadmitted at Dept. of ENT Head & Neck Surgery, AGMC and GBP hospital Agartala, Tripura, India was conducted and bacterial tonsillitis is most common etiology commonly involving the peritonsillar space and Streptococcus pyogenes was found to be most common microorganism associated with DNA. Surgical intervention along with appropriate antimicrobials are mainstay of Treatment of DNA. The main complications of DNA were septic shock.