Abstract: There has a long been proven relationship between obesity and dyslipidemia. Overweight and obesity are disorders of imbalance of energy affecting people of various age groups and socio–economic status. So, hereby we undertook this study to determine the frequency of obesity and its relationship with lipid profile among medical students. Methodology: In this cross sectional study, 300 MBBS students of JMC Jhalawar, Rajasthan in age group 17-30 years were enrolled from period of September 2021 to August 2022.Their height and weight and lipid profile were assessed by using standard methods and techniques. Moreover, on these subjects body mass index (BMI) was calculated and it's association with lipid profile was found. Results: Amongst 300 students, a total of 175(58.3%) were male and 125 (41.7%) were females. Among studied subjects, The prevalence of overweight and obesity was 85 (28.3%) and 10 (3.3%) respectively. Prevalence of Overweight in male and females was 50(16.7%) and 35(11.7%), in obese were 8(2.7%) in male and 2 (0.7%) in female, with more men affected than women. Finding of lipid profile includes mean triglycerides 114.83 ±26.09 mg/dl, total cholesterol 145.96 ±22.02 mg/dl, LDL 102.40 ±14.58 mg/dl, HDL Cholesterol 28.59 ± 9.90 mg/dl, VLDL 23.82 ± 7.95 mg/dl. Obesity was positively association with triglycerides and no. of hypertensive subjects (p<.05%) but showed negative association with total cholesterol, LDL, HDL, VLDL , SBP and DBP (p>.05%). Conclusion: Findings showed males are more prone to be obese and change in the lipid profile is also seen. Though not very significant for all parameters but more on increasing trend. So, Preventive strategies for obesity may offer an early and cost-effective approach towards lowering lipid level and related complications.