Background- Breast cancer is the most common cancer of women worldwide representing approximately16% of all female cancer[1]. It represents the second leading cause of cancer death among women after lung cancer[2], In some of the studies, it occurs secondary to cervical cancer[3,4], presently 75,000 new cases occur in Indian women every year[5]. Aetiology of breast cancer is multifactorial. The present study was done to know the histopathological spectrum of breast malignancies in Ashwini Rural Medical college and research centre, Kumbhari, Solapur. Aim and objectives- This study is aimed to analyse the histopathological spectrum of various breast malignancies and to study the distribution of breast malignancies in different age groups in rural area. Material and methods- After receiving approval of Institutional ethics committee the study was conducted in the histopathology section of our department using the specimens of Modified Radical Mastectomy sent for histopathological evaluations during the mentioned study period. Total 70 specimens were evaluated and the slides were stained with routine stains like H and E. Histo-morphological features as seen in the slides mentioned above were studied and following observations were made. Observations and results-Invasive duct cell carcinoma, 47 cases (66.9%) was the most common malignant breast lesion. Followed by Malignant phyllodestumour which were 10 cases (14.2%). There were 5 cases of Invasive lobular carcinoma and 4 cases of carcinoma in situ. Most number of cases in Invasive ductal carcinoma were of grade 2, followed by grade 1 invasive ductal carcinoma.20 cases of breast carcinoma were of Stage IIA. 14 cases were of stage IIB and stage IIIA. Conclusion-We observed that the females presented at a later stages in the rural areas. It is advisable that awareness should be created about breast health in rural areas and all cases of breast lesions should be carefully evaluated as early as possible to exclude the possibility of malignant breast lesions.