Monoclonal gammopathy of any concentration. It’s a variant of Lymphoplasmacytic lymphoma with Bone marrow involvement & IgM monoclonal gammopathy. Waldenstrom macroglobulinemia constitute around 2% of hematological malignancy. It’s rare slowly progressive disorder with clinical features of Anemia, Thrombocytopenia malignancy, hepatosplenomegaly & lymphadenopathy. The case is remarkable because patient didn’t show any common clinical features of Waldenstrom macroglobulinemia.