Abstract | 10% Lignocaine Spray Versus Eutectic Mixture of 2.5% Lignocaine With 2.5% Prilocaine for Attenuating Venous Cannulation Pain in Adults: A Clinical Comparitive Study

10% Lignocaine Spray Versus Eutectic Mixture of 2.5% Lignocaine With 2.5% Prilocaine for Attenuating Venous Cannulation Pain in Adults: A Clinical Comparitive Study

Background: Venous cannulation is a common yet painful procedure in healthcare settings. This study aimed to compare the efficacy of 10% Lignocaine spray with EMLA cream for pain attenuation during venous cannulation in adults.Methods: A prospective, randomized, comparative study was conducted on 88 adult patients undergoing elective surgeries. Patients were randomly allocated to receive either 10% Lignocaine spray (n=44) or EMLA cream (n=44) prior to venous cannulation. Pain scores were assessed using a visual analog scale (VAS), and hemodynamic parameters were recorded before and after the procedure.Results: The mean pain scores were 2.98 ± 1.45 for the Lignocaine spray group and 3.22 ± 1.38 for the EMLA cream group (p = 0.4287), indicating no significant difference in analgesic efficacy. Hemodynamic parameters, including heart rate, blood pressure, and mean arterial pressure, showed no significant differences between the groups at any time point (p > 0.05 for all comparisons).Conclusion: 10% Lignocaine spray demonstrated comparable efficacy to EMLA cream in reducing venous cannulation pain, with the advantage of a significantly shorter application time. Both methods maintained similar hemodynamic stability and safety profiles.